Indeed, with almost breathtaking speed, a company long viewed as a colossus astride the computer industry is increasingly perceived as a Gulliver, with tribulations that include a courtroom defeat, a swooning stock and defecting employees.

The unexpected courtroom defeat, which blocks Genetics Institute from making or selling the drug in the United States, caused its share price to drop to $40.

While some similar cases have been settled before trial, including a case against Apple Computer, the Brooklyn verdict is the first courtroom defeat for a computer keyboard manufacturer.

Appearing Invincible It was the most stinging courtroom defeat suffered by the Justice Department in its campaign against the Mafia.

In June 1949, faced with the prospect of a courtroom defeat, Chandler offered amnesty to the players who had gone to Mexico.

The Dred Scott decision of 1857, a courtroom defeat for antislavery forces, was a controversial landmark in the public debate.

And the company, now in its ninth year of a 16-year lease at the St. Regis, is not ready to accept its courtroom defeat.

After suffering a courtroom defeat in a major case, it is not unusual for a defendant to bring in additional expertise for the appeals, according to legal experts.

Enforcement Is Tough But the courtroom defeat demonstrated that winning a patent is only half the battle.

The bill is intended to close the so-called loophole, which was central to an important courtroom defeat suffered last month by Amgen over rights to the top-selling anti-anemia drug, erythropoietin, or EPO.