Epigenetic control is often associated with alternative covalent modifications of histones.

Nucleosomes are thought to carry epigenetically inherited information in the form of covalent modifications of their core histones.

NO can also act through covalent modification of proteins or their metal co-factors.

Such covalent modification has an inhibitory effect on these enzymes, thus inhibiting lipogenesis and promoting net gluconeogenesis.

The covalent modifications may change the local or global charge properties of chromosomal proteins and regulate their interactions with DNA.

A significant short-term biochemical change is the covalent modification of pre-existing proteins in order to modify synaptic connections that are already active.

Glycosylation is the most common covalent modification (formation of chemical bonds) that occurs in living organisms.

NO can also act through covalent modification of proteins or their metal co-factors; some have a redox mechanism and are reversible.

The most popular are physical entrapment, adsorption, and covalent modification.

A great deal of recent work explores covalent modification of the bridging ligands.