It has also been shown to enhance the cytotoxic effect of tamoxifen in vitro.
This action might explain the previously observed cytotoxic effect of P. harmala on these cancer cells.
They found that cells halted in S phase were significantly more sensitive to the cytotoxic effects of the drugs.
Usually, in most cases the increased iron concentration in culture media does not lead to cytotoxic effects.
Uranium was shown to have cytotoxic, genotoxic and carcinogenic effects in animal studies.
This could explain the cytotoxic effect of P. harmala on these cells.
Often, it is these cytotoxic effects that lead to the death and decline of a cell infected by a virus.
Later amyloid fiber structures also seem to have some cytotoxic effect on cell cultures.
In those patients who responded to low-dose cytarabine, response appeared to be caused by a cytotoxic effect of the drug.
Compounds that have cytotoxic effects often compromise cell membrane integrity.