They defeated Clemson in the second round before losing to Kentucky in the third round.

In 2009, Georgia Tech defeated Clemson, 39-34, in a matchup of two newcomers to the championship game.

D3 Virginia Tech defeated Clemson in the Gator Bowl, 41-20.

They defeated both Virginia and Clemson on the road, and won the rest of their games by an average of 31 points.

The Bulldogs have national title aspirations and face their most harrowing home opener since 1982, when they defeated Clemson by 13-7.

In his first full season as offensive coordinator, Kentucky finished with a 8-5 record and defeated Clemson in the 2006 Music City Bowl.

Nebraska entered the contest with a 4-game winning streak after defeating Clemson in the Gator Bowl.

Maryland repeated as Atlantic Coast champion again in 2012, defeating Clemson.

Georgia Tech defeated Clemson, winning the Atlantic Coast Conference football championship, 39-34.

Connecticut defeated Clemson in the Regional Final to earn their first trip to a Final Four.