In other first-round games, Evansville beat Marquette, 66-57, Dayton defeated Detroit, 90-72, and Loyola upset St. Louis, 67-58.
It was also fitting that the Terrapins defeated Loyola, 8-7, in the ultimate game.
The final is Sunday with Maryland (18-0) facing Virginia (14-3), which defeated Loyola of Maryland, 10-9.
Detractors point out that the Lions have yet to face a nationally ranked team (St. John's was unranked when it defeated Loyola, 88-85, early in the season).
Lafayette qualified again in 1978 and defeated Loyola (MD) before losing to Monmouth University by one point.
Brown defeated Loyola at Baltimore, 14-13, in overtime.
In another first-round game, Long Island University defeated Loyola of Maryland, 99-90.
Duke defeated Loyola, Notre Dame, Cornell, and Syracuse to capture to their second NCAA Championship.
La Salle (13-1, 4-0) defeated Loyola for the 26th time in 27 games.
Syracuse (8-2); defeated Loyola, 23-13, yesterday; at Pennsylvania, Saturday.