A depression led to alcoholism, which was followed by recovery.

Some researchers feel that depression leads to changes in brain chemistry.

The economic depression of the 1890s led to its closure in 1896.

His depression led him to resign from the band & drop out of the public eye for some time.

An economic recession, depression, or financial crisis could eventually lead to a stock market crash.

This anxiety and depression can then lead back into the health of the caregiver.

In extreme cases, the depression would lead to mental breakdown.

The depression led to additional large numbers of plant closings.

Debilitating depression led him to abandon political office in 1958.

In 1977, depression led him to the brink of shooting himself.