There has to be someone to take over, Angela, as well as someone to end my desperate loneliness.

Terror seized him; and a desperate loneliness in the midst of his social contacts.

But it is more powerful still in the original version, for it immediately follows a scene of desperate loneliness in the pub.

Would he live the rest of his life with such desperate loneliness?

She understood an essentially comic medium in which a simple pause can convey desperate loneliness.

I saw in his burning eyes the piercing desperate loneliness of the man whose race is gone, whose nation is a fantasy.

Or the desperate loneliness that resulted when the close bond of twinship was severed?

Inside, she was sunk in an abyss of deep, desperate loneliness.

And what a desperate loneliness emanates from you.

Charlie had had poverty, and the desperate panic-stricken loneliness of a small child.