A different actress played Aunt May each time she appeared.
Amy was the only character played by two different actresses.
Amelia was played by two different actresses throughout the first few seasons of the show.
This is the third time the character of Sila has been played by a different actress.
The character has been played by 5 different actresses.
Suzanne appears in one third season episode, although played by a different actress.
The role of Margo has been played by four different actresses.
Also, a different actress played the role of Matt's wife.
During the run of the series, she was portrayed by three different actresses.
Four different actresses had the job throughout the show, due to several problems and complications.