Or they might cause disease, including cancer, which certainly would be of direct concern to the recipient.

On the news side, our direct financial concerns are for our annual budget.

Only for a brief moment in history was it of direct concern to mankind.

These are not of direct practical concern to man or his domestic animals.

We care about your security, which is of direct and material concern to us.

But the formulation of these policies was not his direct concern.

"The issue is of no direct concern to us."

We can now move into the specific areas of its direct concerns.

Here is a very practical question, of direct concern to our citizens.

These realities cannot fail to be of direct concern to you.