The disease course in these cases extended over several months.

In some rare patients, these antibodies emerge earlier and can result in a delayed disease course.

In addition, the disease course may be extremely variable from case to case.

Several studies also show diabetes associated with a worse disease course and slower recovery from respiratory infections.

They presented with a very aggressive disease course and, with one exception, died of the lymphoma.

A combination of the above may be necessary early in the disease course.

Life span varies depending on what age the condition started, but the disease course usually runs 3 - 20 or more years.

The disease course of this mutation is extremely long, with the typical time from onset to death being over 15 years.

Metastases are rare at presentation but may occur in up to 30% of patients during the disease course.

Cholinesterase inhibitors are often used early in the disease course.