The domain comprises a six stranded beta sheet of the Rossman fold.
Each domain comprises two β-pleated sheets.
The N-terminal domain comprises 2 alpha-helices and a 5-stranded beta-sheet.
The domain comprises six conserved regions, which in some proteins have considerable insertions between them.
And Hades' domain after all comprises everything that is under the earth.
Marcus prefers an interpretation where the domain of the interpretation comprises individual entities in the actual world.
This domain may also comprise smaller homology domains that are shared with other protein families and superfamilies.
The domain is from position 93 to 194 on the human protein and comprises 43.2% of the sequence.
The domain comprises a number of 48-residue repeats, which themselves contain 3 blocks of 16 residues, the first 8 of which are identical.
The α-helical domain has 310-150 amino acids and comprises four segments in which a seven-residue pattern repeats.