In particular, STAT-3 is activated which leads to the activation of many downstream genes.
Additionally, the fluoride riboswitch and the downstream regulated genes can be potential targets for drug development in the future.
Where are the transcriptional regulatory elements for the downstream gene?
Normally, expression of the downstream genes is suppressed.
In addition, genetic and biochemical approaches have yielded few downstream genes that the key transcription factors regulate.
Biologists hope that by identifying these "downstream" genes, they may be able to unravel the genetic basis of human language.
The aptamers cooperatively bind glycine to regulate the expression of downstream genes.
The result is that the further downstream genes are from the leader sequence, the less they will be transcribed by RNA polymerase.
A polar mutation affects expression of downstream genes or operons.
A riboswitch in Listeria monocytogenes regulates the expression of its downstream gene.