Another, though less noticed controversy he started by expressing his view that drug metabolism is wasted and called for the development of metabolism-resistant drugs.
The decrease is primarily attributed to drug metabolism and excretion.
There are several known genes which are largely responsible for variances in drug metabolism and response.
They are part of the Phase I reactions in drug metabolism.
For the first time, potential drug metabolism and toxicity issues are identified in advance of human clinical trials.
N-Acetyltransferase is important because it acts as an important enzyme of drug metabolism.
Many drug interactions are due to alterations in drug metabolism.
Grapefruit decreased drug metabolism in humans, which likely represented the first clinical example of a food producing such an effect.
Various physiological and pathological factors can also affect drug metabolism.
Pathological factors can also influence drug metabolism, including liver, kidney, or heart diseases.