Repeated low-energy PSR treatment is an effective modality for improving dyspigmentation, smoothness, and skin laxity associated with photoaging.

It may be that the inhibition of the VEGF and Tie2 pathways might be an effective therapeutic modality in RA.

Cryotherapy, an earlier technique in which regional retinal destruction was done using a probe to freeze the desired areas, has also been evaluated in multi-center clinical trials as an effective modality for prevention and treatment of ROP.

A systematic review on the effect of qigong exercises on reducing pain concluded that "the existing trial evidence is not convincing enough to suggest that internal qigong is an effective modality for pain management."

Neuromodulation is emerging as an effective modality to treat patients who are not successful with conservative methods and its demonstrated efficacy has been the topic of multiple publications.

Although questions remain regarding the efficacy of adventure therapy, some research suggests adventure therapy is an effective modality for treatment.

Although there is no evidence that a lactose-restricted diet will prevent radiation enteritis, a diet that is lactose free, low fat, and low residue can be an effective modality in symptom management.

In relaxing tense muscles it would be an effective therapeutic modality.