The process of angioinvasion causes endothelial damage and induces a proinflammatory response, tissue factor expression and activation of the coagulation cascade.

Anticardiolipin antibodies attach to the endothelial lining of cells, causing endothelial damage, platelet aggregation, inflammation, and fibrosis.

Venous thrombi are caused mainly by a combination of venous stasis and hypercoagulability-but to a lesser extent endothelial damage and activation.

Independent of inhibiting the HBP pathway, azarine studies have demonstrated that it can protect against hyperglycemic endothelial damage through its antioxidant effect.

The resistance of those small vessels is determined primarily by the damage on the inner wall (so-called endothelial damage).

Since the process of arteriosclerosis usually begins with endothelial damage, early measurement can only recognize higher AIX (often combined with slightly higher blood pressure).

Activated platelets will adhere, via glycoprotein (GP) Ia, to the collagen that is exposed by endothelial damage.

There is as yet no direct measure of endothelial damage in the intact animal.

It is difficult to determine therefore whether endothelial damage preceded the evidence of enhanced platelet-release reaction or not.

The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage.