As part of the change to the Panther platform, the engine lineup underwent its own downsizing as well.

A major change of the engine lineup was made in 1997; only the 7.3 L diesel remained from the year before.

Changes to the engine lineup happened in the truck's second year on the market.

In 1994, the engine lineup was retuned to increase output.

In the engine lineup, in addition to the existing six-cylinder and V8 engines of the past, new options were added for the 1963 model year.

An expanded engine lineup gave customers six power choices of the six-cylinder or V-8 engines; the four-cylinder was available only in the 100.

For the 2011 model year, an all-new engine lineup was offered.

The engine lineup was revised for 1971, as well.

The engine lineup changed for this year, as well.

The 3800 is notable for being the first American school bus chassis to have an engine lineup consisting only of diesel engines.