It had an enormous effect on Christopher's personality and life.
But the public trial is likely to have an enormous effect in shaping the nation's attitude toward its past.
Both the drug experiments and the job had an enormous effect on Kesey's writing.
The memory had an enormous, purely physical effect on him.
Class size has an enormous effect on school budgets and taxes.
The space itself has an enormous effect on the show.
But it became clear that the deal would have a potentially enormous effect on the company's individual units.
Parents can have such an enormous effect on your lives together that you need to work out the boundaries right at the beginning.
"There's an opportunity for women to show their stuff and I think that alone will have an enormous effect on the private marketplace."
The latter move had an enormous effect on the future of American sports.