Aqueous extracts of the plant inhibited the release of creatine kinase from isolated rat muscle exposed to the crude venom [ 75 ] .
The extracts significantly inhibited the growth and feeding of third instar larvae of Tenebrio molitor (mealworms).
Researchers in 2004 reported that extracts of the fruit body inhibit the enzyme pancreatic lipase; it was the second most inhibitory of 100 mushrooms they tested.
An extract of leaves of Pistacia integerrima also inhibits xanthine oxidase at a level that appears to merit further research.
Laboratory tests have shown that extracts of the fruit bodies can inhibit the growth of several bacteria that are pathogenic to humans.
A further study by the same authors concluded that the extracts also inhibit colon cancer formation associated with colitis in mice.
One study showed that a crude extract of the root bark inhibited 50% of a sample of garden cress (Lepidium sativum) seeds from germinating.
Laboratory tests show that extracts of the plant have some antimicrobial activity and inhibit the formation of biofilms.
One study on O. megacantha raised concern about toxic effects on the kidney and extracts of O. streptacantha may inhibit alpha-glucosidase activity.
In addition, the extract partially inhibited the pro-coagulant activity and completely abolished the degradation of A α chain of human fibrinogen.