The British Government, which supported the laboratory, did not recognize the extraordinary commercial significance of the technique and failed to patent it.

The planet was of extraordinary significance to the Amarantin.

For Joshua, at sixty-two, and suffering from a bad leg, distances had begun to take on an extraordinary significance.

So strong was the impression they left on her mind I think that she quite failed to realize their extraordinary significance!

Oh christ, I'm sure we all recognise her extraordinary significance but admire?

He ascribed extraordinary significance to the medical science, the medical training and the public health.

Events of extraordinary significance, but also of great human tragedy, have put their stamp on the work of the publishing house over two centuries.

It is therefore of extraordinary significance that violence against women and children be made a distinct point on the EU agenda.

Exceptions are made for extraordinary cultural significance.

These cases raise issues of extraordinary significance.