The researchers, who reported on their work in the journal Science, found mutations occurring at a relatively fast clip.
In two patients, 05 and 06, we did not find likely disease-causative mutations despite sequencing all 86 fragments.
Lee et al. used this technology to find mutations that were present in a lung cancer and compared them to normal lung tissue.
In 13 patients they found telltale mutations in the superoxide gene.
But after publication, when the student's senior colleagues checked his results more carefully, they found unnoticed extra mutations.
No matter how hard they looked in many patients who had the severe form of the disease, they could not find mutations in the gene.
It is now possible to find genetic mutations that make people more likely to develop certain cancers.
The authors used various testing techniques beyond the one used by Myriad Genetics and found mutations in 35 of the women.
"You can find mutations that abolish vision or coordination or courtship."
He began cross-breeding experiments to find heritable mutations, but they had no significant success for two years.