Oxford's 60 language schools stress that the country's foremost centre of learning is no more dangerous than most other cities.
It is considered as one of the world's foremost centers of Armenian culture.
The town was also a foremost center of innovation in mining industry.
It is regarded as one of the foremost centres for automotive engine research in Europe.
Mikulčice was also a foremost religious center, with the first stone churches built around 800.
In twelve years they had built Göttingen into one of the world's foremost centres for physics.
In her 21-year tenure the library evolved into one of the nation's foremost centers for women's history.
The town became the foremost Slovak cultural center in the 19th century.
The 18th century saw Amsterdam grow into the foremost financial center in the world, but the seeds of decline had already been planted.
The Eminönü neighborhood was the city's foremost commercial center, and home to a predominantly Jewish population.