The Mediator complex is required for the successful transcription of nearly all class II gene promoters in yeast.
Each of these blocks is preceded by a gene promoter acting as an on/off switch that determines if that particular unit will be expressed or not.
In cultured human neurons, these gene promoters are selectively damaged by oxidative stress.
The 5'-flanking region contains the gene promoter, and may also contain enhancers or other protein binding sites.
Nurr1 interacts with the transcription factor complex NF-κB-p65 on the inflammatory gene promoters.
It is characterized by non-compaction of some gene promoters during mitosis.
Hypermethylation of gene promoters can result in silencing of those genes.
Numbers on the top scale indicate nucleotide positions corresponding to the gene 62 promoter.
The bottom section shows the relative positions of the probe fragments derived from the gene 62 promoter and the restriction sites used for their isolation.
The construction of the polymerase complex takes place on the gene promoter.