Pierre Duhem discussed the possible general significance of this in 1908.

Everything is condensed, simplified, each sequence being utterly specific but also of general significance.

First, as a support for services that have a national or general significance as opposed to being of simply local concern.

But even recurrent sense relations are of varying general significance.

It would seem appropriate to celebrate a few high points from the past, so as to illuminate matters of more general significance.

Also there could be no doubt as to the general significance of the chant by whomsoever it was sung.

The railway used to be of general economic significance for many decades.

The general clinical significance of metformin upon B levels is as yet unknown.

Everything he touched in his particular discipline of anthropology was thus informed by a more general intellectual significance.

It must therefore be acquired and taught in a way which gives it general significance.