While such recipients are more likely to require re-transplantation early on, long-term graft survival is similar to recipients who receive ABOc kidneys.
Retrospective analysis of 67 patients concluded graft survival was similar between reduction and discontinuation of agents.
It is intended to provide extended graft survival while limiting the toxicity generated by standard immune suppressing regimens, such as calcineurin inhibitors.
These cells were isolated from the testis, then added to transplants of the insulin-producing cells of the pancreas (islets of Langerhans), resulting in increased graft survival.
Since zero mismatches have such high graft survival these recipients are afforded priority regardless of location and wait time.
Perfusion devices, often called kidney pumps, can extend graft survival to 36-48 hours post recovery for kidneys.
A number of experimental and clinical studies [ 23 24 ] have demonstrated IL-10 expression to be beneficial and correlates with increased graft survival.
Alcohol and smoking can contribute to poor graft survival.
Different methods have been proposed to further improve graft survival affected by these later factors mainly by removing capture devices and adding/increasing time on ice.
In organ transplantation, belatacept is intended to provide extended graft survival while limiting the toxicity generated by standard immune-suppressing regimens such as calcineurin inhibitors (for example cyclosporin).