Sitting for prolonged periods is a great hindrance to good posture.

A great hindrance to Burundi's economic development is lack of adequate transportation.

If the daggerboard does not fully retract it will be a great hindrance in making progress.

But having parents seemed to us a very great hindrance..

Shields are a great help and a great hindrance to us.

He can show you the way to that which is contrary to the five great hindrances.

Might is a power which is superior to great hindrances.

This is a great hindrance in many areas of research because colour photographs for example, usually provide much more information than black and white photographs.

Napoleon found the mud in Russia to be a very great hindrance in 1812.

The same can be said of Spain, except that their counter-intelligence is a great hindrance to the Party.