"What Indians and buffaloes are doing on the frieze is the greatest puzzle."

Each of us had a piece of the greatest puzzle facing Starfleet.

One of the greatest puzzles in magic was its tendency to occasionally go awry.

And this was going to be the greatest puzzle he'd ever been asked to assemble.

Just what you do have is the greatest puzzle I've faced in years.

The first and greatest puzzle was of course the woman herself.

Perhaps the greatest puzzle of all, however, is essentially political.

The cause of this pattern is one of the greatest puzzles for ecologists today.

And here she was, at the age of six, trying to piece together the greatest puzzle of life.

Astronomers have devised a new method for measuring perhaps the greatest puzzle of our universe - dark energy.