In the second half of the 17th century things changed greatly.

She was now exactly a year old and had changed greatly.

The time of day, at least, had not changed greatly.

"You have not changed so greatly in these few weeks."

But in this way she is greatly changed during the past three weeks.

Her father had changed greatly with his wife's death, too.

She could not speak or understand much, and her character was greatly changed.

The setting is a greatly changed Earth, more than 40 million years in the future.

By the time of David's death, northern art had changed greatly.

Political circumstances changed greatly with the death of the king.