The dust is highly irritating and even stings the skin, but a small price, for such a beautiful timber.

She hadn't even heard him come up from behind, which was highly irritating.

The plant's toxic latex is highly irritating to skin and mucous membranes.

Category I is classified as highly irritating to the eyes, but not to the skin.

The manufacturer's Web site describes "influencing behavior with a highly irritating warning tone."

"And I've found they can be highly irritating."

Exposure to methacrolein is highly irritating to the eyes, nose, throat and lungs.

IF is highly irritating to both the skin and the mucous membranes.

In moderate concentrations it is highly irritating to eyes, nose, and skin.

Those with exposure to highly irritating substances should receive treatment to mitigate harmful effects.