In spite of my efforts to keep my eyes open, they would close.
In spite of their efforts, the fort only lasted a few years.
In spite of all his efforts some people hated him.
But she didn't believe that, in spite of her efforts to convince herself.
The father was finally sent to the chair, in spite of my mother's efforts.
Then they were together once more, all those who remained, joined again in spite of its efforts.
He did this silently, in spite of my best efforts to start a conversation.
In spite of their efforts, they were arrested the next morning on the base.
In spite of his efforts, however, he could not escape.
In spite of their efforts, the city fell to the British.