The inability to form a compromise caused a splintering of the liberals in 1861.
Her inability to function caused him to think about how well Susan was holding up in the situation.
Arguably, her inability to deal with the truth causes her to leave Dan at the end.
The inability to close the mouth causes problems in feeding and speech.
The rising crime figures, and his inability to stem them due to lack of resources, had caused him great distress.
His inability to prove the continuum hypothesis caused him considerable anxiety.
An inability to cool the body through perspiration may cause the skin to feel dry.
The couple's inability to conceive a child has caused increasing tension between them.
Their inability to marry, they said, had caused them legal, financial and emotional harm.
At the local level, too, the inability of probation departments to attract resources is causing frustration.