Control over this new system might ultimately help us lessen the impact of an infection once it's gone on long enough to induce antibodies, but that's a long way from eliminating the common cold.
The vaccine acts by inducing antibodies against both the bacterial components and CTB.
Dr. Grubman said researchers there were "working to develop an improved vaccine, one that induces antibodies to some but not all of the viral proteins."
The polysaccharide antigens were used to induce type-specific antibodies that enhanced opsonization, phagocytosis, and killing of pneumococci by phagocytic cells.
Infection with viral pathogens can induce anti-dsDNA antibodies transiently.
Therefore, a vaccine that could induce antibodies for these antigens could interfere with the hookworm's digestive pathway and impair the worm's survival.
Both vaccines have been shown to induce strong neutralizing antibodies in different laboratory animals.
The Salk vaccine is administered intramuscularly, and being a killed vaccine, predominantly induces systemic antibodies.
It induces warm antibody hemolytic anemia by inducing antibodies to Rh antigens; ibuprofen also does this.
The approval was based on a study of the company's seasonal flu vaccine in children, showing both the vaccine's safety and its ability to induce antibodies expected to protect against influenza.