But Dr Bongiovanni said that, in animal studies, very high doses of the hormone have induced diabetes.

Study 2: Effects of adrenalectomy on hypothalamic responses to insulin deficiency and fasting Streptozotocin injection induced diabetes in sham-operated mice (Table 2).

Their landmark study in 1889 in dogs induced diabetes by removing their pancreas.

Regular wines did not go down well, either, but port proved to be just the thing, sweet enough to soothe his delicate gut but not so sweet as to induce diabetes.

The extract (379 mg/kg) was found to reduce blood glucose levels and slow the development of diabetic nephropathy in mice treated with streptozocin to induce diabetes.

B6 mice develop diet induced diabetes when maintained on a high fat diet [ 76 ] .

A purified extract from prickly pear cactus (Opuntia fuliginosa) controls experimentally induced diabetes in rats.

Due to its high toxicity to beta cells, in scientific researches, streptozotocin has also been long used for inducing insulitis and diabetes on experimental animals.

Because it selectively kills the insulin-producing beta-cells found in the pancreas, alloxan is used to induce diabetes in laboratory animals.

Similarly, conversion from tacrolimus to cyclosporine, most commonly due to tacrolimus induced diabetes, by published report appears to be even rarer.