It cites another study that "found that the odds ratio for finding results favorable to industry in industry-sponsored trials was 3.6 times as high as in non-industry-sponsored studies".
Dr. Wagner's role varied in 12 industry-sponsored trials in which antidepressants were tested against placebos for depression or other problems.
The Journal has been accused of publishing articles that misrepresent the results of industry-sponsored clinical trials.
This case raises questions about many other industry-sponsored clinical trials reported in The Journal and the editor's commitment to enforcing The Journal's conflict of interest policy.
The change reflects testimonials from some patients who seem to have bounced back from their deathbeds, and statements from researchers testing a new class of drugs, known as protease inhibitors, in combination with AZT and other drugs in industry-sponsored trials.
It was found that the odds ratio for finding results favorable to industry in industry-sponsored trials was 3.6 times higher than non-industry-sponsored studies and that 24% of authors did not disclose being funded by the drug companies in their published paper when they were funded by the drug companies.
This web site lists industry-sponsored clinical trials that are actively recruiting patients.
Because the NDA forms the basis for marketing approval, it seems likely that the percentage of industry-sponsored trials that are registered with the FDA is very high.
It was found that the odds ratio for finding results favorable to industry in industry-sponsored trials was 3.6 times higher than non-industry-sponsored studies.
Dr. Wayne K. Goodman, chairman of the Psychopharmacology Advisory Committee, which examines psychiatric drugs, said in an interview that he needed a waiver because a colleague in the psychiatry department at the University of Florida, where he is chairman, was involved in an industry-sponsored trial.