Rats given moexipril one week prior to induction of myocardial infarction, displayed decreased infarct size.

Pre-clinical results suggested that TRO40303 can significantly reduce infarct size following cardiac ischemia-reperfusion.

Reperfusion leads to biochemical imbalances within the cell that lead to cell death and increased infarct size.

The larger the initial infarct size, the greater the effect of the infusion.

Thrombolytic agents might reduce the stimulus to remodelling by limiting infarct size and augmenting blood flow to additional jeopardised zones.

Indeed, the effect of early treatment on infarct size and expansion may be seen only in subgroups of patients, and future studies should be directed at identifying such groups.

The left ventricular ejection fraction correlates only roughly with infarct size, but is a powerful predictor of the long-term survival of the patient following myocardial infarction.

Primary end points of the study were infarct size and ejection fraction, and the results revealed no differences between the groups.

The control animals had no such period of "ischaemic preconditioning" and had much larger infarct sizes compared with the dogs that did.

On myocardial infarct size in acute ischemic dogs].