A modern glass version of an 18th-century European gateway: that's the initial effect.
The advance in industrial production had little initial effect on the credit or stock markets.
"One point four minutes until initial effects, seven minutes before serious radiation."
Its initial effects on demand were much more pronounced.
After the initial effects, however, a user will be drowsy for several hours.
Though it had little initial effect, the impact grew in autumn 1663 and in 1664.
The initial effect of the morphine, if any, had worn off.
There are some herbs that have a strong initial effect, whose potency decreases quickly.
So when they all come in together at the end and play their verses simultaneously the initial effect seems chaotic.
To some, the initial effect, particularly on perimeter walls, is jarring.