Affected children can have serious, irreversible effects or even die within days from birth.

He had been taking a drug that could have caused irreversible and sometimes lethal side effects.

Generally, stunting occurs before the age of 2, with largely irreversible effects.

But during the heat of a test match battle, the instantaneous decision by a captain can have an irreversible effect.

And, as it does so, we believe it may be causing irreversible side effects.

For the biggest area of dispute, aid to schools, the impasse has already had an irreversible effect.

In the year 2058, Earth will soon be uninhabitable after the irreversible effects of pollution.

This shows the knock-on effect of a capital increase and its irreversible effects.

In environmental issues, and I do not know if this is true of other areas, such slow progress can have irreversible effects.

It deals with potential fears for the irreversible effects of judicial activism.