He was the first to show that the kidney toxicity of cisplatin involves reactive oxygen species.
The drug must be administered intravenously, however, and may cause serious kidney toxicity.
The health impacts of these metals on dolphins has been examined and some associations between high metal concentrations and kidney toxicity were noted.
Methicillin was then the antibiotic of choice, but has since been replaced by oxacillin due to significant kidney toxicity.
Patients also taking ciclosporin (Sandimmune) can develop kidney toxicity.
Zometa's label already contains warnings regarding kidney toxicity.
It is also hoped that the drug will have less kidney toxicity than cidofovir.
Trials of PRC200-SS in cynomolgus monkeys showed dose proportional kidney toxicity, with signs that the compound was damaging to the distal tubule and collecting duct.
Gentamicin, which is a commonly used antibiotic for the treatment of severe bacterial infections, can cause kidney toxicity.
Long-term schisandrin B treatment can enhance the resistance of kidney mitochondria to free radicals arising from gentamicin metabolism, thereby protecting against gentamicin-induced kidney toxicity.