The fulling mill at Mill Corner was one of the first large-scale manufacturers of woolen cloth in the country.
Gray & Davison was a large-scale manufacturer of church and cathedral pipe organs, based in London.
After some time he set out on his own, and by the 1890s was a partner in Baker & Creighton, a large-scale manufacturer of shoes.
The company continued to expand following World War II and was a large-scale manufacturer of structural timber, board and other packaging products.
The company added large-scale IT networking manufacturers such as Microsoft, Cisco and Lenovo between 2000 and 2006.
Spratt's was the world's first large-scale manufacturer of dog biscuits.
Wall Street trading firms used the software for trading systems, and eventually, large-scale manufacturers employed the technology as well.
Thetford was home to Tulip International, large-scale manufacturers of bacon, beef and pork.
Tofu is still made by thousands of small, neigborhood shops around Japan, holding their own against the encroachments of large-scale manufacturers.
The lap steel ukulele appears to be a very recent development, with only a handful of professional musicians and large-scale manufacturers addressing the style and instrument.