But as we rush to large-scale release of more and more such organisms, the risk multiplies.

This information exchange is the prelude to what President Clinton hopes will be a large-scale release.

The plan is irreparable for large-scale, rapid releases of the kind that could be caused by a terrorist attack.

First, there is no large-scale release of radiation because the fission reaction is terminated gigaseconds after it starts.

The P.L.O. and its supporters in the territories have been pressing Israel for a large-scale release.

Sandinista groups have staged marches to oppose amnesty for the prisoners and senior leaders have spoken against any large-scale release.

"The questions are very different for a large-scale release," said Amy Rispin, head of a hazard evaluation division at the Environmental Protection Agency.

The study was completed in 1936 and the ban lifted, at which point large-scale releases were undertaken; by March, 1937, 62,000 toadlets had been released into the wild.

But other leaders publicly oppose any large-scale release.

The most improbable would be a large-scale outdoor release of spores by an airplane or sprayer driven around by car or van, experts agreed.