"We weren't ready to play," said Nick Collison, who led Kansas with 19 points.
Ryan Robertson led Kansas to an 11-0 record as a starter at point guard last season.
He led Kansas (18-2, 3-1 Big Eight) with 17 points.
Moody, who led Kansas with 11 points, sprained his ankle soon after his late dunk.
The all-America forward who led Kansas to the national championship last spring, was held scoreless in probably the worst game he has ever played.
Danny Manning led Kansas with 31 points; he fouled out in overtime.
Chamberlain, though, still managed to average nearly 30 points a game, and lead Kansas to a 24-2 record.
Mark Randall, who was selected the tournament's most valuable player, led Kansas with 25 points.
Williams, 52, led Kansas to the Final Four four times, including the past two seasons.
He led Kansas in scoring five times and in assists on 12 occasions.