Naproxcinod was the company's lead compound until 2011.
These compounds had similar, weak herbicidal activity similar to that found with the lead compound.
The key advantage of database searching is that it saves synthetic effort to obtain new lead compounds.
The second method involves mixing the lead compound with silica, which is then placed in suspension and applied directly.
Most countries are stopping leaded fuel use; different additives have replaced the lead compounds.
Many more are hybrids, having been designed following the structure of a natural lead compound.
Researchers can now identify promising protein targets and small sets of chemicals, including good lead compounds, using computation alone.
Animals can sometimes be a source of new lead compounds.
Figure 2 shows the molecular structure of the lead compound and the final compound aplaviroc.
The best of these is generally called the lead compound, while the other will be designated as the "backup".