The strain on his health led to a serious breakdown.

Environmental pollution has led to a breakdown of human civilization.

This was resisted by the singer which led to a breakdown in the relationship.

The scheme led to a large-scale breakdown on the House floor, including a fight between almost all the members of the body.

Differing life priorities have led their marriage to a breakdown.

Criticism of the work led to a nervous breakdown and his working outside music for some time.

After serious division of opinion which nearly led to a complete breakdown, terms were finally signed on October 10.

In a way this led to a breakdown of his body: he could not say no.

If every school chooses their own curriculum then does this not lead to a breakdown in the education system?

That old excuse leads to a breakdown of the moral order.