Yale's league losses were at home to Brown and on the road against third-place Cornell.
Only once in the last 17 seasons has the top-seeded team for the Big East tournament had more than five league losses.
A second league loss for either team will probably take that one out of Ivy championship contention.
It was also his first major league loss.
Although United had many chances in the second half, they failed to beat Wolves, and thus crashed to their first league loss of the season.
Yale's only league loss came against Princeton a week earlier, when it built a 14-point lead at the half before falling, 34-31.
Rusty Meacham (2-1) lasted just two and two-thirds innings in his first major league loss.
Colorado State fell to 0-2, both league losses.
In the end, though, it was the hitter's home run that started the pitcher on the way to his first major league loss.
Connecticut's run of five league losses over three seasons, culminated by its 17-1 record a year ago, now appears an impossible achievement.