Transplant is required when the liver fails and there is no other alternative.
In addition, an overworked liver can eventually fail causing total system collapse.
His liver failed two years ago, eventually requiring him to have a transplant.
If not, then we can discuss me paying you enough money to keep you in Jack until your liver fails.
She realizes the patient's bone marrow is fine, but his liver is failing.
When the liver is failing, the "Valium" goes straight to the brain and knocks the person unconscious.
In 1992 Eddie Hazel died from internal bleeding and his liver failed.
But in at least another 48 percent of the cases studied, the liver failed after a smaller, unintentional assault by the drug over several days.
It appears that House was correct, Abigail's liver is failing.
Jim Wright, calling for vote after vote, looked as if his liver had just failed.