Contact with skin or eyes results in local irritation and pain.

Humans are most notably affected by local irritation, allergic reactions and tick-transmitted infectious diseases.

Irritant plants may cause a local irritation or rash where they come into contact with the skin.

After skin comes in contact with cantharidin, local irritation begins within a few hours.

If you are on a multiple dose (0.25 mg) regimen, choose a different injection site each day to minimize local irritation.

Beryllium can cause local irritation and contact dermatitis.

Cases of local irritation or allergic reaction have been reported; however, these have been mild and infrequent.

Tazarotene can cause a severe local irritation if it is used alone.

Occasional fatalities have been reported, practically without local irritation or olfactory warning.

The most common side effects of sulfacetamide/sulfur combination products are local irritation and contact dermatitis.