During long-duration missions, astronauts will often experience isolation and confinement.

In addition there will be a focus on the psychological aspects of long-duration missions where crew is largely isolated.

Crew rest quarters were included for long-duration missions.

This resulted in 10 broad factors that were deemed important for long-duration missions:

Observers speculate that the flight had a specific objective and was not meant to be a long-duration mission.

Expedition 36 is the 36th and current long-duration mission to the International Space Station.

Lyakhov had been on two spaceflight before, both of which were long-duration missions.

Colonel Afanasyev is a veteran of three long-duration missions.

More generally, the agency is moving toward an era of long-duration missions with crews of men and women.

Additional consideration substantiates the risk of the inability to treat crew members on long-duration missions.