But when a team falters, the threats lose their effect.

He says the prescription drug Enbrel worked for six months, then lost its effect.

It's not something you can do all the time, or it loses its effect.

That, sir, is why I am selling them before they lose their effect.

My father's expression darkened but that seemed to be losing its effect on me.

If you go out in force all the time, it loses its effect.

But the sedatives she had been given would have lost their effect by now.

It wasn't until the evening that these rumors lost their effect.

The story loses its emotional effect because we don't get to know these characters as real people.

At first, they feared that it was losing its effect with her.