A certain number of physical properties also alter with the change from macroscopic systems.

The second law is only applicable to macroscopic systems.

However, they have also demonstrated that quantum violations can be found for arbitrarily large macroscopic systems.

Classical thermodynamics is the study of energy and work in macroscopic systems.

For a macroscopic system this will be a very large dimensionality.

Instead, the energy of such a macroscopic system appears to vary over a continuum of values.

We can verify that our idea of macroscopic systems fall within the correspondence limit.

--- which when stated that way, the answer would be yes for macroscopic systems.

The second law of thermodynamics is a statement about macroscopic systems.

It can be applied to both microscopic and macroscopic systems.