The main sign represents a skull, possibly described as "anthropozoomorphic".

Interestingly, the main sign of living in that kingdom was not good acts or right faith, but what we might call personal integrity.

They are the main sign of physical dependence.

The main sign of melanoma is a change in a mole or other skin growth, such as a birthmark.

Breast development is the main sign that a girl is entering puberty.

An unusually large head is the main sign of congenital hydrocephalus.

In cattle, the main signs of paratuberculosis are diarrhea and wasting.

The main sign of Pentecost in the West is the color red.

The main sign of pneumonia in older adults may be a change in how well they think.

The main sign of a sleep disorder is how you feel during the day.