She was stubbornly optimistic by nature, and found de-pressing situations a major annoyance.
They may be a major annoyance in some circumstances.
I have 2 major annoyances with game reviews.
Time enough to deal with her major annoyance when she knew for certain they wouldn't have to perform any rescue missions.
My test car also didn't have a satellite navigation system, leading to my only major annoyance.
I am a thorn in the Senate's side, you see; a major annoyance to them.
Dandruff is usually harmless, but it can be a major annoyance.
A minor injury is a major annoyance, while a serious one is a disaster.
Those Helsinki Watch people were becoming a major annoyance.
The gift ban was the major annoyance, and conferees could not agree on a bill until late September.